Vasco and Cruzeiro are scheduled to meet at São Januário on 29 August, with both clubs having named their starting elevens ahead of kickoff.
The two sides also have one eye on the Copa do Brasil, giving added importance to the contest.
Preparations were on display at the stadium before kickoff, as both squads wrapped up their warmups.
Managers Pedro Emanuel and Artur Jorge continue a familiar battle that has roots in Portugal, with this fixture being the first time they have clashed on Brazilian soil.
Broadcast details and match odds for the game are listed on the usual channels.
The fixture extends the long story between these two clubs, and both sets of supporters will follow every moment as the managers put their tactical ideas to the test.
Both sides are in contention for a place in the next round, ensuring the final score all the more important.